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Diet’s Impact on Prostate Cancer Management Explored by Expert

Stephen J. Freedland, MD, a urology professor at Cedars-Sinai in Los Angeles, delves into the impact of diet on prostate cancer management. While no specific diet has definitively proven to prevent prostate cancer, observational studies suggest that certain dietary patterns may influence the risk and outcomes of the disease.

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For men without prostate cancer, adopting healthier dietary habits, such as consuming tomatoes and fatty fish while avoiding processed meats, may offer some protection. Conversely, Western-style diets with high inflammatory components were associated with an increased risk of prostate cancer. Interestingly, adherence to a Mediterranean diet was unexpectedly linked to higher localized prostate cancer detection rates, likely due to increased health awareness and screening among those individuals.

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Despite these associations, the effects of dietary choices on prostate cancer risk are relatively modest. While diet can impact inflammation levels and potentially influence disease risk, it is not a definitive preventive measure. Men diagnosed with prostate cancer may find that their dietary choices affect disease progression and survival. Observational studies consistently show that Western and highly processed diets are associated with poorer outcomes, including higher prostate cancer-specific mortality.

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Conversely, following a Mediterranean or plant-based diet was linked to reduced all-cause mortality and potentially slower disease progression, particularly in men under active surveillance. Both plant-based and low-carbohydrate diets that lower insulin levels and inflammation may share similar biological mechanisms, indicating that diet can play a role in managing prostate cancer progression.

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While diet is a crucial component of overall health and well-being for individuals with prostate cancer, Freedland stresses that it should be integrated into a comprehensive treatment strategy. Healthy eating habits can offer some benefits, but they are not a replacement for medical therapy, especially for men with aggressive forms of the disease. Understanding the interplay between diet and prostate cancer outcomes is essential in developing personalized treatment plans for patients.

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Research continues to explore the relationship between dietary patterns and prostate cancer management. A systematic review of prospective cohort studies and clinical trials sheds light on the potential impact of diet on preventing and managing prostate cancer. As the medical community gains further insights into the role of diet in prostate cancer, patients and healthcare providers can leverage this knowledge to optimize treatment strategies and improve patient outcomes.

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